SCHEMBL20766587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20783618	0.90	CYP2D6 (0.41)	CYP2C9CYP2E1CYP3A4CYP2D6CYP2A6
	SCHEMBL20783619	0.85	CYP2A6 (0.35)	CYP2C9CYP2E1CYP3A4CYP2D6CYP2A6
	SCHEMBL20767011	0.81	TAAR1 (0.42)	CYP2C9CYP2E1CYP3A4CYP2D6CYP2A6
	SCHEMBL20767154	0.81	CYP3A4 (0.50)	CYP2C9CYP2E1CYP3A4CYP2D6CYP2A6
	SCHEMBL8224692	0.80	CYP2A6 (0.42)	CYP2C9CYP2E1CYP3A4CYP2D6CYP2A6
	SCHEMBL24538772	0.76	CYP2A6 (0.42)	CYP2C9CYP2E1CYP3A4CYP2D6CYP2A6
	SCHEMBL9603309	0.76	CYP2A6 (0.42)	CYP2C9CYP2E1CYP3A4CYP2D6CYP2A6
	SCHEMBL20766638	0.74	MAPT (0.52)	CYP2E1CYP2D6CYP2A6CYP2B6CYP2C19
	SCHEMBL20766745	0.71	NFKB1 (0.55)	CYP3A4NQO1TYR
	SCHEMBL20767168	0.69	GAA (0.40)	CYP2E1CYP3A4CYP2D6CYP2A6CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.