Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29054770 | 0.82 | MAPK1 (0.39) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL28442300 | 0.74 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL27670508 | 0.71 | MAPK1 (0.37) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL20767247 | 0.71 | MAPK1 (0.34) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL2224338 | 0.71 | — | — | |
| SCHEMBL746387 | 0.70 | EGLN1 (0.52) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL7381744 | 0.70 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL5748166 | 0.70 | MAPK1 (0.33) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL5728913 | 0.70 | MAPK1 (0.37) | MAPK1NFKB1NFKB2RELAUSP2 | |
| SCHEMBL7849903 | 0.69 | MAPK1 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |