Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662187 | 0.75 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL4815113 | 0.71 | P2RX7 (0.34) | MAPK1 | |
| SCHEMBL4675061 | 0.70 | — | — | |
| SCHEMBL20766890 | 0.69 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL4701988 | 0.69 | DAPK3 (0.34) | — | |
| SCHEMBL4674721 | 0.68 | POLB (0.36) | — | |
| SCHEMBL4775253 | 0.67 | GPR119 (0.30) | — | |
| SCHEMBL29054770 | 0.67 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL4698042 | 0.67 | NPSR1 (0.36) | MAPK1 | |
| SCHEMBL28442300 | 0.66 | MAPK1 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082323-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca UK Limited (GB) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999064417-A2 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |