Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.44 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767198 | 0.92 | ALDH1A1 (0.54) | LMNAKDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL20767243 | 0.79 | ALDH1A1 (0.46) | LMNAGAASMN1; SMN2NPSR1HTT | |
| SCHEMBL19554727 | 0.79 | MEN1 (0.68) | LMNAKDM4EGAASMN1; SMN2NPSR1 | |
| SCHEMBL20766914 | 0.77 | HTR2A (0.54) | LMNAKDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL339704 | 0.73 | TACR1 (0.55) | L3MBTL1HTR2ATACR1 | |
| SCHEMBL8669485 | 0.72 | ALDH1A1 (0.61) | LMNAKDM4ESMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL20767214 | 0.72 | STS (0.53) | LMNASMN1; SMN2HTTALDH1A1SLC2A1 | |
| SCHEMBL20766347 | 0.72 | ALDH1A1 (0.52) | LMNAKDM4ESMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL15453328 | 0.70 | PYCR1 (0.55) | LMNAKDM4EGAASMN1; SMN2NPSR1 | |
| SCHEMBL20774962 | 0.70 | HTR2A (0.60) | HTR2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | claimed |