Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767197 | 0.90 | HTR2A (0.48) | ALDH1A1HTR2AYAP1TEAD4TEAD2 | |
| Hydrochloric Acid SCHEMBL20766904 | 0.89 | HTR2A (0.48) | ALDH1A1HTR2AYAP1TEAD4TEAD2 | |
| SCHEMBL20767225 | 0.88 | HTR2A (0.54) | HTR2ASLC6A2SLC6A4SLC6A3NPSR1 | |
| SCHEMBL20767249 | 0.85 | HTR2A (0.52) | SMN1; SMN2TAS2R14CHRM2CHRM1CHRM3 | |
| SCHEMBL20767198 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TAS2R14CHRM2CHRM1 | |
| SCHEMBL20781013 | 0.81 | HTR2A (0.57) | HTR2ANPSR1 | |
| SCHEMBL20767227 | 0.80 | SLC6A2 (0.44) | ALDH1A1SMN1; SMN2HTR2ATSHRSLC6A2 | |
| SCHEMBL20767211 | 0.79 | LMNA (0.54) | ALDH1A1SMN1; SMN2TAS2R14HTR2ASLC2A1 | |
| SCHEMBL339704 | 0.78 | TACR1 (0.55) | HTR2ASLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL20767191 | 0.78 | HTR2A (0.57) | ALDH1A1SMN1; SMN2CHRM1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | claimed |
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |
| WO-2019040105-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |