Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767914 | 0.81 | ALDH1A1 (0.38) | TXNRD1TXNRD3TXNRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3661945 | 0.74 | AKR1B1 (0.36) | ALDH1A1SMN1; SMN2TDP1HTTMEN1 | |
| SCHEMBL2002714 | 0.71 | RIPK1 (0.52) | TXNRD1TXNRD3TXNRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29361660 | 0.71 | RIPK1 (0.52) | TXNRD1TXNRD3TXNRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL20588775 | 0.69 | CYP19A1 (0.48) | ALDH1A1SMN1; SMN2TDP1HTTCYP3A4 | |
| SCHEMBL1247145 | 0.68 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2TDP1HTTCYP3A4 | |
| SCHEMBL1137222 | 0.66 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TDP1HTTCYP3A4 | |
| SCHEMBL239666 | 0.65 | CYP19A1 (0.52) | ALDH1A1SMN1; SMN2TDP1HTTCYP3A4 | |
| Dinitrophenylene SCHEMBL10796281 | 0.64 | MAPT (0.55) | ALDH1A1SMN1; SMN2TDP1HTTCYP3A4 | |
| SCHEMBL24603533 | 0.64 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TDP1HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221168-B1 | Small-compound enhancers for functional O-mannosylation of alpha-dystroglycan, and uses thereof | Wu, Xiao Hua (US) | 2019-03-05 | — | — | US | disclosed |
| US-10221168-B1 | Small-compound enhancers for functional O-mannosylation of alpha-dystroglycan, and uses thereof | Wu, Xiao Hua (US) | 2019-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221168-B1 | Small-compound enhancers for functional O-mannosylation of alpha-dystroglycan, and uses thereof | MAN2A1, MAN1B1, ALG1 | TXNRD1 4534/4885TXNRD3 4435/4885TXNRD2 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.