Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptobenzothiazole SCHEMBL28269969 | 0.89 | MMP13 (0.66) | MAPTKMT2AMEN1MAPK1NPSR1 | |
| 2-Mercaptobenzothiazole SCHEMBL28269970 | 0.83 | KMT2A (0.53) | MAPTKMT2AMEN1MAPK1NPSR1 | |
| 2-Mercaptobenzothiazole SCHEMBL17391213 | 0.83 | MMP13 (0.49) | MAPTKMT2AMEN1MAPK1NPSR1 | |
| 2-Mercaptobenzothiazole SCHEMBL17391215 | 0.83 | MMP13 (0.49) | MAPTKMT2AMEN1MAPK1NPSR1 | |
| SCHEMBL29361660 | 0.81 | RIPK1 (0.52) | MAPTKMT2AMAPK1MMP13APP | |
| SCHEMBL2002714 | 0.81 | RIPK1 (0.52) | MAPTKMT2AMAPK1MMP13APP | |
| SCHEMBL1247145 | 0.81 | SMN1; SMN2 (0.67) | MAPTKMT2AMEN1ALDH1A1TSHR | |
| 2-Mercaptobenzothiazole SCHEMBL23237 | 0.79 | ALDH1A1 (0.54) | MAPTKMT2AMEN1MAPK1APP | |
| 2-Mercaptobenzothiazole SCHEMBL29509878 | 0.79 | ALDH1A1 (0.54) | MAPTKMT2AMEN1MAPK1APP | |
| 2-Mercaptobenzothiazole SCHEMBL3789760 | 0.79 | ALDH1A1 (0.54) | MAPTKMT2AMEN1MAPK1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4672025-A | BLACK AND WHITE PHOTOGRAPHIC DEVELOPER CONTAINING A CHELATING AGENT; AUTOMATIC PROCESSING | FUJI PHOTO FILM CO., LTD. (JP) | 1987-06-09 | — | — | US | disclosed |