Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763726 | 0.83 | CHRNB2 (0.56) | CHRNB2CHRNA4ALDH1A1KDM4ELTA4H | |
| SCHEMBL27816979 | 0.80 | CARM1 (0.35) | ALDH1A1KDM4EHRH3CARM1PRMT6 | |
| SCHEMBL2645780 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4ECARM1PRMT6PRMT8 | |
| SCHEMBL188508 | 0.79 | HRH3 (0.60) | KDM4EHRH3PYCR1TSHR | |
| SCHEMBL18227681 | 0.78 | MEN1 (0.47) | ALDH1A1KDM4ELTA4HHRH3CARM1 | |
| SCHEMBL162718 | 0.78 | HRH3 (0.56) | CHRNB2CHRNA4ALDH1A1HRH3TSHR | |
| SCHEMBL3038304 | 0.77 | CARM1 (0.41) | ALDH1A1KDM4ECARM1PRMT6PRMT8 | |
| SCHEMBL12910454 | 0.76 | CHRNB2 (0.50) | CHRNB2CHRNA4ALDH1A1KDM4ELTA4H | |
| SCHEMBL355111 | 0.76 | TSHR (0.61) | CHRNB2CHRNA4ALDH1A1KDM4ECARM1 | |
| SCHEMBL27625032 | 0.76 | HRH3 (0.54) | CHRNB2CHRNA4ALDH1A1HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1393131-A | Antifungal triazole compounds | MILITARY MEDICAL UNIV NO 2 P L (CN) | 2003-01-29 | — | — | CN | claimed |
| US-10604525-B2 | Pyrazolopyrimidine derivatives | BAYAL ANIMAL HEALTH GMBH (DE) | 2020-03-31 | — | — | US | disclosed |
| US-20190071447-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604525-B2 | Pyrazolopyrimidine derivatives | P2RX5, RECQL, P2RX1 | CHRNB2 3776/4885CHRNA4 2589/4885ALDH1A1 1297/4885 |
| US-20190071447-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | P2RX5, RECQL, P2RX1 | CHRNB2 3776/4885CHRNA4 2589/4885ALDH1A1 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.