Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | TOP1 | P11387 | 3/20 | 0.63 |
| ▸ | TOP2A | P11388 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769012 | 0.94 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14665474 | 0.91 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL19484925 | 0.90 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL6530109 | 0.90 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL340370 | 0.89 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL29350619 | 0.89 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL617906 | 0.89 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL3171446 | 0.89 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL21017604 | 0.89 | DGAT1 (0.63) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL21847754 | 0.88 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213546-B2 | Methods to mobilize tissue resident cells for adoptive t cell therapy | EMORY UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-20190070221-A1 | Methods to Mobilize Tissue Resident Cells for Adoptive T Cell Therapy | EMORY UNIVERSITY | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070221-A1 | Methods to Mobilize Tissue Resident Cells for Adoptive T Cell Therapy | CD69, CD47, ICOS | ALDH1A1 3002/4885SMN1; SMN2 1343/4885TOP1 2213/4885 |
| US-11213546-B2 | Methods to mobilize tissue resident cells for adoptive t cell therapy | CD69, CD47, ICOS | ALDH1A1 3002/4885SMN1; SMN2 1343/4885TOP1 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.