Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | TOP1 | P11387 | 3/20 | 0.61 |
| ▸ | TOP2A | P11388 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.56 |
| ▸ | TERT | O14746 | 4/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768152 | 0.89 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL19484925 | 0.89 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL617906 | 0.88 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL29350619 | 0.88 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL26252732 | 0.88 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL3171446 | 0.88 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL21017604 | 0.87 | DGAT1 (0.63) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL21847754 | 0.87 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL1439775 | 0.87 | TOP1 (0.79) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| Hoechst 33258 SCHEMBL5682613 | 0.86 | TOP1 (0.78) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723139-B1 | CELL TARGETING CONJUGATES | PETER MACCALLUM CANCER INST (AU) | 2014-01-01 | — | — | EP | disclosed |
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |
| US-8097238-B2 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE (AU) | 2012-01-17 | — | — | US | disclosed |
| US-8008522-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2011-08-30 | — | — | US | disclosed |
| US-8008522-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2011-08-30 | — | — | US | disclosed |
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2010-10-14 | — | — | US | disclosed |
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2010-10-14 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-7671218-B2 | Phosphonate fluorescent dyes and conjugates | Elitech Holdings B.V. (NL) | 2010-03-02 | — | — | US | disclosed |
| US-7671218-B2 | Phosphonate fluorescent dyes and conjugates | Elitech Holdings B.V. (NL) | 2010-03-02 | — | — | US | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-20070140970-A1 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | ALDH1A1 946/4885SMN1; SMN2 4028/4885TOP1 817/4885 |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | ALDH1A1 1457/4885SMN1; SMN2 4304/4885TOP1 916/4885 |
| US-20070140970-A1 | Cell targeting conjugates | CD47, CD74, CD2 | ALDH1A1 1727/4885SMN1; SMN2 3773/4885TOP1 158/4885 |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | ALDH1A1 946/4885SMN1; SMN2 4028/4885TOP1 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.