Phosphoric Acid

Phosphoric Acid

SCHEMBL4575893

O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@]2(O)F)c(=O)[nH]1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.53
SLC28A2 O43868 1/20 0.53
SLC29A1 Q99808 1/20 0.53
SLC28A3 Q9HAS3 1/20 0.53
POLA1 P09884 1/20 0.52
P2RY2 P41231 6/20 0.51
P2RY4 P51582 2/20 0.51
P2RY14 Q15391 4/20 0.48
P2RY6 Q15077 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL20769291 1.00 SLC28A1 (0.53) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
Phosphoramidic Acid SCHEMBL17439381 0.95 SLC29A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
SCHEMBL1763360 0.95 SLC29A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
SCHEMBL8749574 0.95 SLC29A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
SCHEMBL7876363 0.95 SLC29A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
SCHEMBL233416 0.95 SLC29A1 (0.57) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
Hydrochloric Acid SCHEMBL29938288 0.94 SLC29A1 (0.56) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
Phosphoric Acid SCHEMBL21751466 0.89 SLC29A1 (0.55) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
Phosphoric Acid SCHEMBL21489124 0.86 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3POLA1
Phosphoric Acid SCHEMBL21489185 0.86 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11041151-B2 RNA array compositions and methods WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-06-22 US disclosed
US-10167474-B2 Cell-specific internalizing RNA aptamers against human CCR5 and uses therefore CITY OF HOPE (US) 2019-01-01 US disclosed
US-20180112211-A1 RNA Array Compositions and Methods NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-04-26 US disclosed
US-20180080026-A1 CELL-SPECIFIC INTERNALIZING RNA APTAMERS AGAINST HUMAN CCR5 AND USES THEREFORE THE SCRIPPS RESEARCH INSTITUTE 2018-03-22 US disclosed
US-9605266-B2 Cell-specific internalizing RNA aptamers against human CCR5 and uses therefore CITY OF HOPE (US) 2017-03-28 US disclosed
US-20160193202-A1 THERAPEUTIC TREATMENT FOR DRUG POISONING AND ADDICTION ADISPELL, INC. 2016-07-07 US disclosed
US-20160053265-A1 CELL-SPECIFIC INTERNALIZING RNA APTAMERS AGAINST HUMAN CCR5 AND USES THEREFORE THE SCRIPPS RESEARCH INSTITUTE 2016-02-25 US disclosed
WO-2015023664-A2 THERAPEUTIC TREATMENT FOR DRUG POISONING AND ADDICTION ADISPELL, INC. (US) 2015-02-19 WO disclosed
US-20140235505-A1 RNA ARRAY COMPOSITIONS AND METHODS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-08-21 US disclosed
WO-2014011768-A1 ANTI-ANXIETY TREATMENT ADISPELL, INC. (US) 2014-01-16 WO disclosed
US-5958691-A DETECTION OF NUCLEIC ACID LIGANDS WITH MODIFIED NUCLEOTIDE TO TARGET GROUPS, SINGLE STRAND NUCLEIC ACIDS AND PARTITIONING THE NUCLEIC ACIDS, AMPLIFICATION NEXSTAR PHARMACEUTICALS, INC. (US) 1999-09-28 US disclosed
US-5817635-A RNA MOLECULES WITH CATALYTIC ACTIVITY MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1998-10-06 US disclosed
US-5698687-A RNA MOLECULE CONTAINING MODIFIED NUCLOSIDE MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1997-12-16 US disclosed
US-5672695-A GENETIC ENGINEERED RNA MOLECULE, ATLEAST ONE MODIFIED NUCLEOSIDE HAVING A HALO, AMINO, MONO OR DISUBSTITUTED AMINO AND AZIDE MODIFIER GROUPS REPLACING HYDROXY GROUP AT 2' POSITION OF DRIBOSE SUGAR; SHOWS CATALYTIC ACTIVITY MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1997-09-30 US disclosed
US-5660985-A CONTACTING MIXTURE OF MODIFIED SINGLE-STRANDED NUCLEIC ACIDS WITH TARGET MOLECULE, PARTITIONING THOSE WITH INCREASED AFFINITY, AMPLIFYING TO IDENTIFY LIGANDS OF TARGET MOLECULE NEXSTAR PHARMACEUTICALS, INC. (US) 1997-08-26 US disclosed
EP-0552178-B1 MODIFIED RIBOZYMES MAX PLANCK GESELLSCHAFT (DE) 1997-01-02 EP disclosed
EP-0724647-A1 NUCLEIC ACID LIGANDS AND IMPROVED METHODS FOR PRODUCING THE SAME NeXstar Pharmaceuticals, Inc. (US) 1996-08-07 EP disclosed
WO-1995007364-A1 NUCLEIC ACID LIGANDS AND IMPROVED METHODS FOR PRODUCING THE SAME NEXSTAR PHARMACEUTICALS, INC. (US) 1995-03-16 WO disclosed
EP-0552178-A1 MODIFIED RIBOZYMES. MAX PLANCK GESELLSCHAFT (DE) 1993-07-28 EP disclosed
WO-1992007065-A1 MODIFIED RIBOZYMES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1992-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160193202-A1 THERAPEUTIC TREATMENT FOR DRUG POISONING AND ADDICTION CHRNG, CHRM3, CHRNA5 SLC28A1 1247/4885SLC28A2 1195/4885SLC29A1 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.