Phosphoramidic Acid

Phosphoramidic Acid

SCHEMBL17439381

NP(=O)(O)O.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@]2(O)F)c(=O)[nH]1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.51
SLC28A1 O00337 1/20 0.51
SLC28A2 O43868 1/20 0.51
SLC28A3 Q9HAS3 1/20 0.51
POLA1 P09884 1/20 0.51
P2RY2 P41231 5/20 0.49
P2RY4 P51582 2/20 0.49
P2RY14 Q15391 4/20 0.47
PDE4D Q08499 1/20 0.44
PDE3A Q14432 1/20 0.44
P2RY6 Q15077 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4575893 0.95 SLC28A1 (0.53) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Phosphoric Acid SCHEMBL20769291 0.95 SLC28A1 (0.53) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL7876363 0.93 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL8749574 0.93 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL1763360 0.93 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL233416 0.93 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Hydrochloric Acid SCHEMBL29938288 0.92 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL17439383 0.86 POLA1 (0.60) POLA1P2RY2P2RY4P2RY14P2RY6
Phosphoric Acid SCHEMBL21751466 0.85 SLC29A1 (0.55) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL17184312 0.84 PDE3A (0.67) SLC29A1SLC28A1SLC28A2SLC28A3POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160016986-A1 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT ACHILLION PHARMACEUTICALS, INC. 2016-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016986-A1 STABILIZED NUCLEOTIDES FOR MEDICAL TREATMENT NUDT1, DUT, ADAR SLC29A1 51/4885SLC28A1 130/4885SLC28A2 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.