Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.69 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802423 | 0.87 | PTGDR2 (0.61) | PTGDR2PLA2G2ATHRATHRBMEN1 | |
| SCHEMBL4209387 | 0.83 | PTGDR2 (0.74) | PTGDR2PLA2G2ATHRATHRBMEN1 | |
| SCHEMBL1940199 | 0.82 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL13802422 | 0.82 | PTGDR2 (0.76) | PTGDR2PLA2G2ATHRATHRBMEN1 | |
| SCHEMBL4270126 | 0.80 | THRA (0.71) | PTGDR2PLA2G2ATHRATHRBMEN1 | |
| SCHEMBL13802405 | 0.80 | PTGDR2 (0.70) | PTGDR2PLA2G2ATHRATHRBPLA2G1B | |
| SCHEMBL4211522 | 0.80 | PTGDR2 (0.72) | PTGDR2PLA2G2ATHRATHRBMEN1 | |
| SCHEMBL19064547 | 0.79 | CYP1A2 (0.71) | PTGDR2PLA2G2AMEN1ALDH1A1KMT2A | |
| SCHEMBL19088055 | 0.78 | GFER (0.54) | PTGDR2PLA2G2ATHRBMEN1ALDH1A1 | |
| SCHEMBL20787987 | 0.78 | ALDH1A1 (0.54) | MEN1ALDH1A1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046668-A1 | AMIDE SUBSTITUTED THIAZOLES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-03-07 | — | — | WO | disclosed |