Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715 | 1.00 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL67237 | 1.00 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL65737 | 1.00 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL29757088 | 1.00 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL9171150 | 0.98 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| Methane SCHEMBL7338694 | 0.98 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL16820451 | 0.98 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL2008283 | 0.98 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL5598361 | 0.98 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL29272545 | 0.98 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929209-A | Treatment of amyotrophic lateral sclerosis | 艾米利克斯制药公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-3675838-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | Puretecch LYT, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |