Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65737 | 0.98 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL67237 | 0.98 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL20769804 | 0.98 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL29757088 | 0.98 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL1715 | 0.98 | LMNA (0.59) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL9171150 | 0.96 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL16820451 | 0.96 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL2008283 | 0.96 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| SCHEMBL5598361 | 0.96 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB | |
| Phosphine SCHEMBL28961689 | 0.96 | LMNA (0.58) | LMNAHSD17B10CYP2C19ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790136-A | Preparation method and application of active trivalent organic chromium compound | 中国石油天然气股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| EP-0048433-B1 | NOVEL AMIDINE COMPOUNDS, PROCESS FOR PRODUCING SAME AND ANTI-COMPLEMENT AGENT COMPRISING THEM | TORII & CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |
| US-4532255-A | Amidine compounds and anticomplement agent comprising same | TORII & CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| US-4454338-A | 6-AMIDINO-2-NATHTHYL-4-GUANIDINOBENZOATE | TORII & CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | disclosed |