SCHEMBL67237

SCHEMBL67237

CC[C@H](C(=O)O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
HSD17B10 Q99714 1/20 0.59
CYP2C19 P33261 1/20 0.57
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
CRHBP P24387 2/20 0.53
CRHR2 Q13324 2/20 0.53
KCNQ2 O43526 2/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
KDM4A O75164 1/20 0.51
BCHE P06276 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HTR1A P08908 1/20 0.51
ADRA1A P35348 1/20 0.51
CYP2D6 P10635 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1715 1.00 LMNA (0.59) LMNAHSD17B10CYP2C19ALDH1A1POLB
SCHEMBL20769804 1.00 LMNA (0.59) LMNAHSD17B10CYP2C19ALDH1A1POLB
SCHEMBL65737 1.00 LMNA (0.59) LMNAHSD17B10CYP2C19ALDH1A1POLB
SCHEMBL29757088 1.00 LMNA (0.59) LMNAHSD17B10CYP2C19ALDH1A1POLB
SCHEMBL9171150 0.98 LMNA (0.58) LMNAHSD17B10CYP2C19ALDH1A1POLB
Methane SCHEMBL7338694 0.98 LMNA (0.58) LMNAHSD17B10CYP2C19ALDH1A1POLB
Hydrochloric Acid SCHEMBL16820451 0.98 LMNA (0.58) LMNAHSD17B10CYP2C19ALDH1A1POLB
Hydrochloric Acid SCHEMBL2008283 0.98 LMNA (0.58) LMNAHSD17B10CYP2C19ALDH1A1POLB
SCHEMBL5598361 0.98 LMNA (0.58) LMNAHSD17B10CYP2C19ALDH1A1POLB
SCHEMBL29272545 0.98 LMNA (0.58) LMNAHSD17B10CYP2C19ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108546720-B Method for preparing (S) -2-phenylbutyric acid through stereoselective enzymatic hydrolysis 湖南理工学院 2021-09-03 CN claimed
CN-113278604-A Method for hydrolyzing and splitting 2-phenylbutyric acid enantiomer by using immobilized lipase as catalyst 湖南理工学院 2021-08-20 CN claimed
CN-108546720-A A kind of method that stereoselectivity enzymatic hydrolysis prepares (S) -2- phenylbutyric acids 湖南理工学院 2018-09-18 CN claimed
EP-0862549-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS UNION CARBIDE CHEM PLASTIC (US) 2000-05-31 EP claimed
CN-1204314-A Process for preparing optically active carboxylic acids UNION CARBIDE CHEM PLASTIC (US) 1999-01-06 CN claimed
EP-0862549-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-09-09 EP claimed
US-5739385-A OXIDIZING AN OPTICALLY ACTIVE ALDEHYDE WITH A PERACID IN THE PRESENCE OF AN AMINE AND/OR AMINE N-OXIDE CATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-04-14 US claimed
WO-1997014669-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-04-24 WO claimed
EP-4545138-A1 HETEROCYCLIC COMPOUNDS AS BLT2 AGONISTS AND THEIR MEDICAL USE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-04-30 EP disclosed
US-11697636-B2 Substituted benzamides HOFFMANN-LA ROCHE INC. (US) 2023-07-11 US disclosed
US-20230210808-A1 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS CYMABAY THERAPEUTICS, INC. 2023-07-06 US disclosed
US-20230210808-A1 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS CYMABAY THERAPEUTICS, INC. 2023-07-06 US disclosed
EP-3187490-B1 SUBSTITUTED BENZAMIDE DERIVATIVES HOFFMANN LA ROCHE (CH) 2022-04-06 EP disclosed
EP-3676263-B1 3-HYDROXY-IMIDAZOLIDIN-4-ONE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE NETHERLANDS TRANSLATIONAL RES CENTER B V (NL) 2021-10-06 EP disclosed
CN-1055181-A SELECTIVE ADENOSINE RECEPTOR AGENTS MERRELL DOW PHARMA (US) 1991-10-09 CN disclosed
EP-0449175-A2 Selective adenosine receptor agents MERRELL PHARMACEUTICALS INC. (US) 1991-10-02 EP disclosed
US-5047534-A Xanthine derivatives; hyupotensive agents, cardiotonic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1991-09-10 US disclosed
US-4997844-A Compounds for the treatment of allergic or inflammatory diseases or shock conditions ICI AMERICAS INC. (US) 1991-03-05 US disclosed
EP-0348901-A2 Process for producing optically active alfa-substituted organic acid and microorganism and enzyme used therefor Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-01-03 EP disclosed
US-4851344-A Microbial reduction of monocarboxylic and dicarboxylic acids in the presence of carbon monoxide and/or formates plus mediators BASF AKTIENGESELLSCHAFT (DE) 1989-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210808-A1 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS PPARA, PPARG, PPARD LMNA 2274/4885HSD17B10 331/4885CYP2C19 3032/4885
US-11697636-B2 Substituted benzamides TAAR1, TAAR5, NPY1R LMNA 3001/4885HSD17B10 1311/4885CYP2C19 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.