Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bropirimine SCHEMBL4058 | 1.00 | XDH (0.57) | XDHFGFR1FGFR2ALDH1A1HPGD | |
| Bropirimine SCHEMBL5271073 | 0.82 | XDH (0.41) | XDHFGFR1FGFR2ALDH1A1HPGD | |
| SCHEMBL19665218 | 0.81 | MAPK13 (0.54) | XDHALDH1A1HPGDKDM4EPLA2G10 | |
| SCHEMBL8995841 | 0.81 | XDH (0.49) | XDHFGFR1FGFR2ALDH1A1HPGD | |
| SCHEMBL15928125 | 0.79 | KDM4E (0.56) | XDHALDH1A1HPGDKDM4EPLA2G10 | |
| SCHEMBL19733297 | 0.76 | XDH (0.60) | XDHALDH1A1HPGDADORA2AADORA1 | |
| SCHEMBL5383500 | 0.74 | MAPK13 (0.60) | ALDH1A1HPGDHSD17B10MAPTMAPK13 | |
| Bropirimine SCHEMBL509127 | 0.72 | XDH (1.00) | XDHFGFR1FGFR2ALDH1A1HPGD | |
| SCHEMBL725362 | 0.72 | KDM4E (0.60) | XDHALDH1A1HPGDKDM4EGAA | |
| SCHEMBL31683723 | 0.71 | XDH (0.46) | XDHFGFR1FGFR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675838-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | Puretecch LYT, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| CN-109988240-A | Anti- GPC-3 antibody and application thereof | 安源生物科技(上海)有限公司 | 2019-07-09 | — | — | CN | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |