Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772240 | 0.81 | GABRG2 (0.44) | ALDH1A1GLP1RMAPTKDM4EHSD17B10 | |
| SCHEMBL20775292 | 0.73 | PTPN1 (0.33) | GLP1RHPGDHTT | |
| SCHEMBL20775013 | 0.72 | ALDH1A1 (0.41) | ALDH1A1CYP1A2GLP1RMAPTKDM4E | |
| SCHEMBL20771884 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL20775924 | 0.70 | CNR1 (0.36) | ALDH1A1KDM4ENPSR1KMT2A | |
| SCHEMBL20785461 | 0.70 | GLP1R (0.44) | ALDH1A1CYP1A2GLP1RMAPTKDM4E | |
| SCHEMBL19740351 | 0.70 | RAB9A (0.51) | ALDH1A1CYP1A2MAPTKDM4EHSD17B10 | |
| SCHEMBL8143037 | 0.69 | ALDH1A1 (0.47) | ALDH1A1CYP1A2GLP1RMAPTKDM4E | |
| SCHEMBL1795334 | 0.69 | TARBP2 (0.44) | ALDH1A1CYP1A2GLP1RMAPTKDM4E | |
| SCHEMBL26281309 | 0.69 | ALDH1A1 (0.52) | ALDH1A1CYP1A2GLP1RMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675856-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046784-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | CORVUS PHARMACEUTICALS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |