Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17984429 | 0.93 | PTGDR2 (0.49) | S1PR5S1PR1PTGDR2 | |
| SCHEMBL505382 | 0.85 | PPARA (0.50) | S1PR5S1PR1PTGDR2 | |
| SCHEMBL504679 | 0.84 | S1PR5 (0.52) | S1PR5S1PR1S1PR3 | |
| SCHEMBL23012259 | 0.84 | S1PR5 (0.48) | S1PR5S1PR1S1PR3 | |
| SCHEMBL29479760 | 0.84 | S1PR5 (0.48) | S1PR5S1PR1S1PR3 | |
| SCHEMBL505149 | 0.83 | GRM5 (0.49) | S1PR5PTGDR2 | |
| SCHEMBL29479674 | 0.81 | S1PR5 (0.47) | S1PR5S1PR1PTGDR2S1PR3 | |
| SCHEMBL17982156 | 0.80 | S1PR5 (0.46) | S1PR5PTGDR2 | |
| SCHEMBL504497 | 0.80 | S1PR5 (0.48) | S1PR5S1PR1PTGDR2S1PR3 | |
| SCHEMBL505215 | 0.80 | GRM5 (0.56) | S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227362-B2 | Anti-pulmonary tuberculosis nitroimidazole derivative | MEDSHINE DISCOVERY INC. (CN) | 2019-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227362-B2 | Anti-pulmonary tuberculosis nitroimidazole derivative | NDUFV1, NDUFV2, MT-ND4 | S1PR5 4688/4885S1PR1 4761/4885PTGDR2 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.