Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20769894 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL22844182 | 0.83 | CXCR4 (0.63) | SMN1; SMN2TP53KMT2APOLBMAPT | |
| SCHEMBL2031432 | 0.80 | CXCR4 (0.62) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL1520593 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL4897865 | 0.76 | LMNA (0.71) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL7746045 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL21877941 | 0.76 | LMNA (0.43) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL1520364 | 0.74 | POLB (0.69) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL1520758 | 0.74 | ALDH1A1 (0.76) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL1520195 | 0.74 | POLB (0.73) | SMN1; SMN2TP53RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046364-A1 | INHIBITORS OF RSV REPLICATION AND APPLICATIONS THEREOF | EMORY UNIVERSITY (US) | 2019-03-07 | — | — | WO | disclosed |