Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 15/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779762 | 0.90 | OPRK1 (0.43) | OPRK1POLBRXFP1 | |
| SCHEMBL20766548 | 0.80 | BRD4 (0.49) | OPRK1POLBRXFP1 | |
| SCHEMBL20766476 | 0.78 | PTGS2 (0.42) | OPRK1POLBRXFP1 | |
| SCHEMBL30410749 | 0.78 | PTGS2 (0.42) | OPRK1POLBRXFP1 | |
| SCHEMBL20779695 | 0.74 | OPRK1 (0.46) | OPRK1 | |
| SCHEMBL20779645 | 0.71 | IRAK1 (0.41) | — | |
| SCHEMBL20779658 | 0.71 | AXL (0.49) | — | |
| SCHEMBL20384219 | 0.70 | ALDH1A1 (0.43) | — | |
| SCHEMBL20779889 | 0.70 | OPRK1 (0.35) | OPRK1 | |
| SCHEMBL19931287 | 0.70 | SMN1; SMN2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |