Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779546 | 0.84 | YAP1 (0.37) | YAP1HDAC8ALOX15MAPTKDM4E | |
| SCHEMBL20779666 | 0.82 | YAP1 (0.36) | YAP1HDAC8ALOX15MAPTKDM4E | |
| SCHEMBL20779858 | 0.82 | YAP1 (0.36) | YAP1HDAC8ALOX15MAPTKDM4E | |
| SCHEMBL20779491 | 0.82 | YAP1 (0.36) | YAP1HDAC8ALOX15MAPTKDM4E | |
| SCHEMBL20779561 | 0.81 | YAP1 (0.38) | YAP1HDAC8ALOX15IDO1HSP90AA1 | |
| SCHEMBL20779550 | 0.80 | YAP1 (0.34) | YAP1HDAC8ALOX15GAAKMT2A | |
| SCHEMBL20779677 | 0.80 | YAP1 (0.34) | YAP1HDAC8ALOX15HSP90AA1CA1 | |
| SCHEMBL20779729 | 0.80 | ALOX15 (0.35) | YAP1ALOX15CA1CA2CA3 | |
| SCHEMBL20779784 | 0.77 | YAP1 (0.37) | YAP1HDAC8ALOX15MAPTKDM4E | |
| SCHEMBL21925800 | 0.76 | MAPT (0.51) | YAP1HDAC8ALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |