Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | GPR39 | O43194 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779631 | 0.86 | GPR39 (0.42) | KDM4ENUDT1GPR39ADORA2AADORA1 | |
| SCHEMBL20779638 | 0.85 | GPR39 (0.37) | KDM4EGAAMAPTNUDT1GPR39 | |
| SCHEMBL20779785 | 0.81 | GPR39 (0.49) | KDM4EGAAMAPTGPR39IDO1 | |
| SCHEMBL30411424 | 0.79 | ALOX15 (0.41) | KDM4EGAAMAPTALOX15PIM1 | |
| SCHEMBL20766349 | 0.79 | ALOX15 (0.41) | KDM4EGAAMAPTALOX15PIM1 | |
| SCHEMBL21925800 | 0.78 | MAPT (0.51) | KDM4EGAAMAPTNUDT1ALOX15 | |
| SCHEMBL20779779 | 0.77 | IRAK1 (0.40) | MAPTADORA2AADORA1LMNA | |
| SCHEMBL20779742 | 0.76 | FLT3 (0.34) | KDM4EMAPTGPR39ADORA2AADORA1 | |
| SCHEMBL20779692 | 0.75 | LATS1 (0.43) | KDM4EGAAMAPTADORA2AADORA1 | |
| SCHEMBL20779876 | 0.74 | ALDH1A1 (0.32) | KDM4EMAPTGPR39ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |