Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSH | P09668 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levopropylhexedrine SCHEMBL161851 | 1.00 | CTSK (0.42) | CTSKSIGMAR1MEN1KMT2ACTSL | |
| Propylhexedrine SCHEMBL28537 | 1.00 | CTSK (0.42) | CTSKSIGMAR1MEN1KMT2ACTSL | |
| Propylhexedrine SCHEMBL28890426 | 0.98 | CTSK (0.41) | CTSKSIGMAR1MEN1KMT2ACTSL | |
| Propylhexedrine SCHEMBL4900116 | 0.98 | CTSK (0.41) | CTSKSIGMAR1MEN1KMT2ACTSL | |
| Cyclopentamine SCHEMBL13479599 | 0.98 | CTSK (0.40) | CTSKSIGMAR1MEN1KMT2ACTSL | |
| Cyclopentamine SCHEMBL249708 | 0.98 | CTSK (0.40) | CTSKSIGMAR1MEN1KMT2ACTSL | |
| Cyclopentamine SCHEMBL317336 | 0.95 | CTSK (0.39) | CTSKSIGMAR1MEN1KMT2ACTSL | |
| SCHEMBL27308544 | 0.93 | — | — | |
| SCHEMBL22627190 | 0.81 | CTSK (0.32) | CTSK | |
| SCHEMBL23241391 | 0.79 | OPRK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046287-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING OR PREVENTING HEPATITIS B | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-03-07 | — | — | WO | disclosed |