Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 11/20 | 0.51 |
| ▸ | MEP1A | Q16819 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15762363 | 0.83 | LMNA (0.66) | LMNA | |
| SCHEMBL20794226 | 0.82 | MEP1B (0.54) | MEP1BMEP1AMRGPRX4TP53PKM | |
| SCHEMBL13180006 | 0.82 | HSD17B2 (0.47) | LMNA | |
| SCHEMBL4407864 | 0.80 | MEP1B (0.65) | MEP1BMEP1AMRGPRX4TP53PKM | |
| SCHEMBL13227044 | 0.79 | MEP1B (0.50) | MEP1BMEP1AMRGPRX4TP53PKM | |
| SCHEMBL15142867 | 0.77 | FOLH1 (0.54) | MEP1BMEP1APPARGMRGPRX4TP53 | |
| SCHEMBL29630981 | 0.75 | FOLH1 (0.59) | MEP1BMEP1AMRGPRX4TP53PKM | |
| SCHEMBL168738 | 0.75 | FOLH1 (0.59) | MEP1BMEP1AMRGPRX4TP53PKM | |
| SCHEMBL4018145 | 0.74 | LMNA (0.56) | RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL29690742 | 0.73 | FOLH1 (0.58) | MEP1BMEP1AMRGPRX4TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043018-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) | 2019-03-07 | — | — | WO | disclosed |