Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776120 | 0.86 | SMN1; SMN2 (0.45) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL31258510 | 0.84 | KDM4E (0.44) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL27471350 | 0.83 | ALDH1A1 (0.49) | MAPTNPC1RAB9ATDP1ABL1 | |
| SCHEMBL15451126 | 0.82 | NPC1 (0.47) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL28211396 | 0.80 | KDM4E (0.62) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL15541724 | 0.79 | KDM4E (0.54) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL26132505 | 0.79 | TTBK1 (0.52) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL1787738 | 0.79 | MAPT (0.67) | MAPTKDM4ENPC1RAB9APOLB | |
| SCHEMBL9208872 | 0.79 | POLB (0.55) | KDM4EPOLBABL1ALDH1A1L3MBTL1 | |
| SCHEMBL31633499 | 0.79 | GAA (0.61) | MAPTKDM4EPOLBABL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103414-B | Substituted benzamides for arthropod processing | 拜耳作物科学股份公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-106103414-A | The substituted benzamides processed for arthropod | 拜耳作物科学股份公司 | 2016-11-09 | — | — | CN | disclosed |
| US-20120178726-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178726-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-07-12 | — | — | US | disclosed |
| US-20120178726-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-07-12 | — | — | US | disclosed |
| US-8163724-B2 | Glucocorticosteroids, processes for their preparation, pharmaceutical compositions containing them and their use in therapy | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |
| US-8163724-B2 | Glucocorticosteroids, processes for their preparation, pharmaceutical compositions containing them and their use in therapy | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |
| US-8163724-B2 | Glucocorticosteroids, processes for their preparation, pharmaceutical compositions containing them and their use in therapy | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |
| CN-101883778-A | Steroidal [3, 2-C] pyrazole compounds, with glucocorticoid activity | ASTRAZENECA AB | 2010-11-10 | — | — | CN | disclosed |
| US-20090286835-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-11-19 | — | — | US | disclosed |
| US-20090286835-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-11-19 | — | — | US | disclosed |
| US-20090286835-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-11-19 | — | — | US | disclosed |
| WO-2009044200-A1 | STEROIDAL [3, 2-C] PYRAZOLE COMPOUNDS, WITH GLUCOCORTICOID ACTIVITY | ASTRAZENECA AB (SE) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178726-A1 | NOVEL COMPOUNDS | F12, C1R, CXCR4 | MAPT 3720/4885KDM4E 1428/4885NPC1 1079/4885 |
| US-20090286835-A1 | NOVEL COMPOUNDS | F12, C1R, CXCR4 | MAPT 3720/4885KDM4E 1428/4885NPC1 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.