SCHEMBL31258510

SCHEMBL31258510

CNc1ccc(F)c(C(=O)OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
POLB P06746 1/20 0.44
ATM Q13315 1/20 0.44
ALDH1A1 P00352 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HPGD P15428 2/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
MAPT P10636 4/20 0.43
CASP3 P42574 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
CDK1 P06493 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ABL1 P00519 1/20 0.41
CA12 O43570 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4833247 0.86 SMN1; SMN2 (0.46) KDM4EPOLBATMALDH1A1L3MBTL1
SCHEMBL2078044 0.84 MAPT (0.45) KDM4EPOLBATMALDH1A1L3MBTL1
SCHEMBL27471350 0.81 ALDH1A1 (0.49) ALDH1A1L3MBTL1HPGDTSHRHSD17B10
SCHEMBL9208872 0.80 POLB (0.55) KDM4EPOLBALDH1A1L3MBTL1HPGD
SCHEMBL16669803 0.80 ALDH1A1 (0.46) KDM4EALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL112046 0.79 CES2 (0.61) KDM4EALDH1A1L3MBTL1HPGDTSHR
SCHEMBL12853005 0.79 EGFR (0.55) KDM4EPOLBATMALDH1A1L3MBTL1
SCHEMBL11983335 0.79 TTBK1 (0.50) KDM4EPOLBATMALDH1A1HPGD
SCHEMBL12611683 0.79 MEN1 (0.63) KDM4EPOLBALDH1A1L3MBTL1TSHR
SCHEMBL1401556 0.78 KDM4E (0.58) KDM4EPOLBATMALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695247-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
WO-2024213662-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed