Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057087 | 0.85 | MAOA (0.58) | RAB9ASMN1; SMN2SCN9ADAOMAOB | |
| SCHEMBL28024514 | 0.83 | ALDH1A1 (0.51) | CYP2A6TDP1RAB9AHTTALDH1A1 | |
| SCHEMBL28024975 | 0.82 | MAOB (0.57) | CYP2A6RAB9ACYP1A2MAOBMAOA | |
| SCHEMBL28386710 | 0.82 | MAOB (0.57) | CYP2A6TDP1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL28389508 | 0.82 | MAOA (0.57) | CYP2A6RAB9AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL11601101 | 0.80 | ALDH1A1 (0.56) | RAB9AHTTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL3380070 | 0.79 | MAOA (0.58) | RAB9AHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10661141 | 0.79 | SLC6A4 (0.53) | TDP1RAB9AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL19422820 | 0.78 | MAOA (0.41) | CYP2A6RAB9AALDH1A1CYP1A2SCN9A | |
| SCHEMBL14189345 | 0.78 | DAO (0.46) | RAB9AHTTALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752708-B2 | Curable composition, cured product and optical member | NIKON CORPORATION (JP) | 2020-08-25 | — | — | US | disclosed |
| CN-104892471-B | Substance having protein tyrosine kinase inhibitory activity, preparation method and use thereof | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 2020-03-27 | — | — | CN | disclosed |
| US-20190071522-A1 | CURABLE COMPOSITION, CURED PRODUCT AND OPTICAL MEMBER | NIKON CORPORATION (FR) | 2019-03-07 | — | — | US | disclosed |
| CN-104892471-A | Substances having protein tyrosine kinase inhibitory activity, and preparation method and use thereof | INST RADIATION MED AMMS PLA | 2015-09-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071522-A1 | CURABLE COMPOSITION, CURED PRODUCT AND OPTICAL MEMBER | FANCI, WDR1, C5 | CYP2A6 1808/4885TDP1 2876/4885RAB9A 3388/4885 |
| US-10752708-B2 | Curable composition, cured product and optical member | FANCI, WDR1, C5 | CYP2A6 1808/4885TDP1 2876/4885RAB9A 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.