Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057087 | 0.85 | MAOA (0.58) | MAOBMAOAANPEPRAB9A | |
| SCHEMBL31468135 | 0.84 | MAOB (0.50) | MAOBMAOACYP2A6ANPEPRAB9A | |
| SCHEMBL28024503 | 0.83 | CYP2A6 (0.47) | MAOBMAOACYP2A6ANPEP | |
| SCHEMBL28386710 | 0.82 | MAOB (0.57) | MAOBMAOACYP2A6ANPEPCYP1A2 | |
| SCHEMBL28389508 | 0.82 | MAOA (0.57) | MAOBMAOACYP2A6ANPEPRAB9A | |
| SCHEMBL20780451 | 0.82 | CYP2A6 (0.50) | MAOBMAOACYP2A6ANPEPCYP1A2 | |
| SCHEMBL28024991 | 0.80 | MAOB (0.51) | MAOBMAOAMGAMGAASI | |
| SCHEMBL845713 | 0.79 | MAOB (0.59) | MAOBMAOACYP1A2 | |
| SCHEMBL19422820 | 0.78 | MAOA (0.41) | MAOBMAOACYP2A6ANPEPCYP1A2 | |
| SCHEMBL31307765 | 0.77 | CYP1A2 (0.44) | MAOBMAOACYP2A6ANPEPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892471-B | Substance having protein tyrosine kinase inhibitory activity, preparation method and use thereof | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 2020-03-27 | — | — | CN | disclosed |
| CN-104892471-A | Substances having protein tyrosine kinase inhibitory activity, and preparation method and use thereof | INST RADIATION MED AMMS PLA | 2015-09-09 | — | — | CN | disclosed |