Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FOS | P01100 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766408 | 0.84 | HTR2A (0.49) | XDHHTR2AACACBFOSJUN | |
| SCHEMBL30523654 | 0.84 | HTR2A (0.49) | XDHHTR2AACACBFOSJUN | |
| SCHEMBL3727305 | 0.80 | KMT2A (0.45) | KMT2AMEN1PKMXDHSMN1; SMN2 | |
| SCHEMBL3718801 | 0.78 | ALDH1A1 (0.41) | KMT2AXDHSMN1; SMN2POLBFOS | |
| SCHEMBL3940925 | 0.76 | ACACB (0.49) | KMT2AMEN1SMN1; SMN2ACACBPOLB | |
| SCHEMBL23182931 | 0.75 | ALDH1A1 (0.40) | KMT2AXDHSMN1; SMN2POLBFOS | |
| SCHEMBL10921397 | 0.75 | FAAH (0.47) | KMT2AMEN1FOSJUNALDH1A1 | |
| SCHEMBL2958827 | 0.74 | NR1H4 (0.51) | XDHMCL1POLBFOSJUN | |
| SCHEMBL27864666 | 0.74 | GABRA1 (0.45) | HTR2ALMNAESR1 | |
| SCHEMBL8483862 | 0.73 | TDP1 (0.47) | KMT2AMEN1SMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040104-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |