Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385652 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL30775081 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL20781141 | 0.83 | HCRTR1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL7901595 | 0.76 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL30775065 | 0.72 | ALDH1A1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3388543 | 0.72 | ALDH1A1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3387269 | 0.69 | HCRTR2 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL27831836 | 0.68 | HDAC4 (0.45) | — | |
| SCHEMBL30775053 | 0.68 | HCRTR2 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL2471955 | 0.68 | HCRTR2 (0.42) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043407-A1 | SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTANE AND 2-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS | CHRONOS THERAPEUTICS LIMITED (GB) | 2019-03-07 | — | — | WO | disclosed |