Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.37 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775065 | 0.77 | ALDH1A1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3388543 | 0.77 | ALDH1A1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3385652 | 0.76 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL30775081 | 0.76 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL20780879 | 0.76 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL13637232 | 0.75 | NOS3 (0.42) | HCRTR1HCRTR2POLB | |
| SCHEMBL26521057 | 0.70 | CCR1 (0.50) | — | |
| SCHEMBL27831836 | 0.69 | HDAC4 (0.45) | HDAC4 | |
| SCHEMBL15230506 | 0.68 | METAP2 (0.59) | — | |
| SCHEMBL15539272 | 0.67 | MBOAT4 (0.41) | MBOAT4HEXAHEXBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063663-A1 | N-{[(IR,4S,6R-3-(2-PYRIDINYLCARBONYL)-3-AZABICYCLO [4.1.0]HEPT-4-YL] METHYL}-2-HETEROARYLAMINE DERIVATIVES AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2010-06-10 | — | — | WO | disclosed |