Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20783917 | 0.89 | ROCK2 (0.63) | ROCK2ROCK1 | |
| SCHEMBL20774709 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL20774601 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL20783998 | 0.77 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL20774820 | 0.73 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL21573654 | 0.70 | ROCK2 (0.60) | ROCK2ROCK1 | |
| SCHEMBL21573532 | 0.70 | ROCK2 (0.60) | ROCK2ROCK1 | |
| SCHEMBL21573645 | 0.70 | ROCK2 (0.62) | ROCK2ROCK1 | |
| SCHEMBL21573606 | 0.70 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL24464181 | 0.67 | GALR2 (0.44) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019045824-A1 | INHIBITORS OF RHO ASSOCIATED COILED-COIL CONTAINING PROTEIN KINASE | KADMON CORPORATION, LLC (US) | 2019-03-07 | — | — | WO | disclosed |