Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LIG1 | P18858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20787622 | 0.88 | TLR4 (0.35) | MAPTALDH1A1HTTCYP1A2CYP3A4 | |
| SCHEMBL20787606 | 0.81 | SMN1; SMN2 (0.43) | MAPTALDH1A1HTTGAACYP1A2 | |
| SCHEMBL20786864 | 0.78 | SMN1; SMN2 (0.45) | MAPTALDH1A1HTTGAACYP1A2 | |
| SCHEMBL20764511 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1HTTGAACYP1A2 | |
| SCHEMBL20764503 | 0.75 | EP300 (0.41) | ALDH1A1GAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20786866 | 0.74 | SMN1; SMN2 (0.44) | MAPTALDH1A1HTTGAAPOLB | |
| SCHEMBL20787426 | 0.73 | SMN1; SMN2 (0.42) | MAPTALDH1A1HTTGAACYP1A2 | |
| SCHEMBL20786871 | 0.71 | NPC1 (0.39) | MAPTALDH1A1HTTGAAPOLB | |
| SCHEMBL22100074 | 0.71 | ALDH1A1 (0.37) | ALDH1A1GAACYP3A4MEN1KMT2A | |
| SCHEMBL31311025 | 0.69 | LMNA (0.45) | MAPTALDH1A1HTTGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |