Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764511 | 0.90 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRCYP3A4EP300 | |
| SCHEMBL20764572 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRCYP3A4ADRB2 | |
| SCHEMBL20764555 | 0.80 | SMN1; SMN2 (0.44) | ALDH1A1HSD17B10TSHRADRB2ADRB1 | |
| SCHEMBL15956250 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E | |
| SCHEMBL20764503 | 0.75 | EP300 (0.41) | ALDH1A1CYP3A4EP300ADRB2ADRB1 | |
| SCHEMBL17368445 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRCYP3A4ADRB2 | |
| SCHEMBL31311112 | 0.73 | MAPT (0.41) | ALDH1A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL31311198 | 0.73 | MAPT (0.48) | ALDH1A1TSHRCYP3A4KDM4ETP53 | |
| SCHEMBL20786864 | 0.73 | SMN1; SMN2 (0.45) | ALDH1A1HSD17B10CYP3A4ADRB2ADRB1 | |
| SCHEMBL15956132 | 0.72 | NPC1 (0.41) | ALDH1A1HSD17B10TSHRCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034648-B2 | Cystobactamide derivatives | HELMHOLTZ-ZENTRUM FÜR (DE) | 2021-06-15 | — | — | US | disclosed |
| US-20200190020-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034648-B2 | Cystobactamide derivatives | CTH, CBS, SLC7A11 | ALDH1A1 2016/4885HSD17B10 1012/4885TSHR 1997/4885 |
| US-20200190020-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | CTH, CBS, SLC7A11 | ALDH1A1 2382/4885HSD17B10 1026/4885TSHR 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.