SCHEMBL2079544

SCHEMBL2079544

CC1(C)CCc2[c]cccc21

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL815280 0.89 KDM1A (0.34)
SCHEMBL8308882 0.73 TP53 (0.32) TP53CYP1A2
SCHEMBL5543310 0.68 IDO1 (0.35) TP53CYP1A2
SCHEMBL9856648 0.68 KDM1A (0.33)
SCHEMBL15192055 0.67 PGR (0.30)
SCHEMBL412891 0.66 KDM1A (0.48) TP53
SCHEMBL27908726 0.66 KDM1A (0.48) TP53
SCHEMBL29529565 0.66 KDM1A (0.48) TP53
SCHEMBL9770695 0.65 ALDH1A1 (0.37) TP53
SCHEMBL501768 0.65 RXRA (0.42) TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373191-B1 ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS SANOFI AVENTIS DEUTSCHLAND (DE) 2013-06-05 EP claimed
US-8163751-B2 Acylated indanyl amines and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2012-04-24 US claimed
US-20100183712-A1 ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2010-07-22 US claimed
US-20070082897-A1 ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-04-12 US claimed
EP-1390337-A1 PRECURSORS FOR KETONES AND ALDEHYDES Givaudan SA (CH) 2004-02-25 EP claimed
US-20030055093-A1 Acylated indanyl amines and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2003-03-20 US claimed
WO-2002096850-A1 PRECURSORS FOR KETONES AND ALDEHYDES GIVAUDAN SA (CH) 2002-12-05 WO claimed
EP-0087000-B1 N-OXALYL DERIVATIVES OF N-METHYL CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1985-11-13 EP claimed
US-4507292-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1985-03-26 US claimed
US-4281011-A Insecticidal N-methyl-N-(benzene sulfonic acid methylamide-N'-sulfenyl)-carbamic acid oxime esters BAYER AKTIENGESELLSCHAFT (DE) 1981-07-28 US claimed
US-4113876-A INSECTICIDES, FUNGICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-12 US claimed
EP-3823955-A1 alfa, alfa-DISUBSTITUTED CARBOXYLIC ACID ESTERS FOR USE AS AROMA CHEMICALS BASF SE (DE) 2021-05-26 EP disclosed
EP-3802758-A1 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS BASF SE (DE) 2021-04-14 EP disclosed
WO-2020016421-A1 α, α-DISUBSTITUTED CARBOXYLIC ACID ESTERS FOR USE AS AROMA CHEMICALS BASF SE (DE) 2020-01-23 WO disclosed
WO-2019224373-A1 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS BASF SE (DE) 2019-11-28 WO disclosed
US-4212883-A HERBICIDE, INSECTICIDE, ACARICIDE, NEMATOCIDE, FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4212887-A NEMATOCIDES, INSECTICIDES, MITICIDES, APHIDICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
US-4148910-A NEMATICIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed
US-4113876-A INSECTICIDES, FUNGICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-12 US disclosed
US-3954836-A INSECTICIDES, ACARICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100183712-A1 ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS EDNRA, EDNRB, VEGFA TP53 3860/4885CYP1A2 315/4885
US-20030055093-A1 Acylated indanyl amines and their use as pharmaceuticals EDNRA, VEGFA, EDNRB TP53 4448/4885CYP1A2 298/4885
US-20070082897-A1 ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS EDNRA, EDNRB, VEGFA TP53 3862/4885CYP1A2 306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.