Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPI1 | P60174 | 2/20 | 0.54 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | PGK2 | P07205 | 1/20 | 0.46 |
| ▸ | PGD | P52209 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CTH | P32929 | 1/20 | 0.41 |
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MVD | P53602 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoglycolic Acid SCHEMBL380471 | 1.00 | — | — | |
| Phosphoglycolic Acid SCHEMBL5586781 | 0.97 | TPI1 (0.52) | TPI1PGK1PGK2PGDTSHR | |
| Phosphoglycolic Acid SCHEMBL29156120 | 0.97 | TPI1 (0.52) | TPI1PGK1PGK2PGDTSHR | |
| Phosphoglycolic Acid SCHEMBL9172688 | 0.95 | TPI1 (0.50) | TPI1PGK1PGK2PGDTSHR | |
| Phosphoglycolic Acid SCHEMBL27464510 | 0.95 | TPI1 (0.50) | TPI1PGK1PGK2PGDTSHR | |
| Phosphoglycolic Acid SCHEMBL3972924 | 0.92 | TPI1 (0.48) | TPI1PGK1PGK2PGDTSHR | |
| SCHEMBL8852887 | 0.82 | MVD (0.42) | TPI1PGK1PGK2PGDTSHR | |
| 3-Phosphoglyceric Acid SCHEMBL8006738 | 0.81 | PGK1 (0.81) | TPI1PGK1PGK2PGD | |
| Phosphoglycolic Acid SCHEMBL19253821 | 0.81 | TPI1 (0.39) | TPI1PGK1PGK2PGDTDP1 | |
| SCHEMBL5485133 | 0.79 | TPI1 (0.56) | TPI1PGK1PGK2PGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3679065-A1 | SIGNALING AND ANTIGEN-PRESENTING BIFUNCTIONAL RECEPTORS (SABR) | California Institute of Technology (US) | 2020-07-15 | — | — | EP | disclosed |
| WO-2019051001-A1 | SIGNALING AND ANTIGEN-PRESENTING BIFUNCTIONAL RECEPTORS (SABR) | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-03-14 | — | — | WO | disclosed |