Phosphoglycolic Acid

Phosphoglycolic Acid

SCHEMBL3972924

O=C(O)COP(=O)(O)O.OB(O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TPI1 P60174 2/20 0.48
▸ PGK1 P00558 1/20 0.41
▸ PGK2 P07205 1/20 0.41
▸ PGD P52209 3/20 0.39
▸ TSHR P16473 2/20 0.36
▸ CTH P32929 1/20 0.36
▸ CBS P35520 1/20 0.36
▸ THPO P40225 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ BLM P54132 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ MVD P53602 2/20 0.35
▸ THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoglycolic Acid SCHEMBL380471 0.92 — —
Phosphoglycolic Acid SCHEMBL20798069 0.92 TPI1 (0.54) TPI1PGK1PGK2PGDTSHR
Phosphoglycolic Acid SCHEMBL29156120 0.90 TPI1 (0.52) TPI1PGK1PGK2PGDTSHR
Phosphoglycolic Acid SCHEMBL5586781 0.90 TPI1 (0.52) TPI1PGK1PGK2PGDTSHR
Phosphoglycolic Acid SCHEMBL9172688 0.87 TPI1 (0.50) TPI1PGK1PGK2PGDTSHR
Phosphoglycolic Acid SCHEMBL27464510 0.87 TPI1 (0.50) TPI1PGK1PGK2PGDTSHR
SCHEMBL8852887 0.76 MVD (0.42) TPI1PGK1PGK2PGDTSHR
3-Phosphoglyceric Acid SCHEMBL8006738 0.74 PGK1 (0.81) TPI1PGK1PGK2PGD
Phosphoglycolic Acid SCHEMBL19253821 0.74 TPI1 (0.39) TPI1PGK1PGK2PGDTDP1
SCHEMBL5485133 0.73 TPI1 (0.56) TPI1PGK1PGK2PGDBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1506786-B1 MEDICINAL COMPOSITIONS CONTAINING GHRELIN DAIICHI SANKYO CO LTD (JP) 2016-11-23 — — EP claimed
US-8518893-B2 Medical compositions containing ghrelin ASUBIO PHARMA CO. LTD. (JP) 2013-08-27 — — US claimed
US-8440628-B2 stable aqueous solution containing endogenous growth hormone secretagogues having pH range of 2 to 7; a pH adjuster or a buffer agent; nondegradation, storage stability; biodrug inducing the secretion of growth hormone DAIICHI SANKYO COMPANY, LIMITED (JP) 2013-05-14 — — US claimed
US-20120264691-A1 MEDICAL COMPOSITIONS CONTAINING GHRELIN KENJI KANGAWA (JP) 2012-10-18 — — US claimed
CN-100411683-C Medicinal compositions containing ghrelin DAIICHI SUNTORY PHARMA CO LTD (JP) 2008-08-20 — — CN claimed
US-20080081787-A1 Medical compositions containing ghrelin Kangawa, Kenji (JP) 2008-04-03 — — US claimed
US-20060166871-A1 Medical compositions containing ghrelin DAIICHI SUNTORY PHARMA., LTD. (JP) 2006-07-27 — — US claimed
CN-1622822-A Medicinal compositions containing ghrelin DAIICHI SUNTORY PHARMA CO LTD (JP) 2005-06-01 — — CN claimed
EP-1506786-A1 MEDICINAL COMPOSITIONS CONTAINING GHRELIN Daiichi Suntory Pharma Co., Ltd. (JP) 2005-02-16 — — EP claimed
US-20040110845-A1 Stabilized albuterol compositions and method of preparation thereof DEY, L.P. 2004-06-10 — — US claimed
US-20040109826-A1 Stabilized albuterol compositions and method of preparation thereof DEY, L.P. 2004-06-10 — — US claimed
US-11931422-B2 Antibody-urease conjugates for therapeutic purposes HELIX BIOPHARMA CORPORATION (CA) 2024-03-19 — — US disclosed
EP-3261678-B1 ANTIBODY-UREASE CONJUGATES FOR THERAPEUTIC PURPOSES HELIX BIOPHARMA CORP (CA) 2020-11-11 — — EP disclosed
US-20200261541-A1 METHODS OF TREATING MILD BRAIN INJURY OXEIA BIOPHARMACEUTICALS, INC. (US) 2020-08-20 — — US disclosed
CN-110382551-A Anti-VEGFR-2 urase conjugate 赫利克斯生物药品公司 2019-10-25 — — CN disclosed
EP-1506786-A1 MEDICINAL COMPOSITIONS CONTAINING GHRELIN Daiichi Suntory Pharma Co., Ltd. (JP) 2005-02-16 — — EP disclosed
EP-1506786-A1 MEDICINAL COMPOSITIONS CONTAINING GHRELIN Daiichi Suntory Pharma Co., Ltd. (JP) 2005-02-16 — — EP disclosed
US-20040110845-A1 Stabilized albuterol compositions and method of preparation thereof DEY, L.P. 2004-06-10 — — US disclosed
US-20040109826-A1 Stabilized albuterol compositions and method of preparation thereof DEY, L.P. 2004-06-10 — — US disclosed
WO-2003097083-A1 MEDICINAL COMPOSITIONS CONTAINING GHRELIN DAIICHI SUNTORY PHARMA CO.,LTD. (JP) 2003-11-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200261541-A1 METHODS OF TREATING MILD BRAIN INJURY FABP7, PYGB, ATP6V1B2 TPI1 4596/4885PGK1 1901/4885PGK2 1769/4885
US-11931422-B2 Antibody-urease conjugates for therapeutic purposes SLC14A1, UNG, UPP1 TPI1 775/4885PGK1 3225/4885PGK2 3035/4885
US-20040110845-A1 Stabilized albuterol compositions and method of preparation thereof ALB, CMA1, ADRB2 TPI1 2776/4885PGK1 2440/4885PGK2 2475/4885
US-20040109826-A1 Stabilized albuterol compositions and method of preparation thereof ALB, CMA1, ADRB2 TPI1 2776/4885PGK1 2440/4885PGK2 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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