SCHEMBL20798887

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18081561	0.85	PTGS1 (0.46)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL17527969	0.84	AKT1 (0.48)	AKT1ALDH1A1HPGDMAPTKDM4E
	SCHEMBL17175665	0.83	SIGMAR1 (0.41)	PTGS1PTGS2AKT1MGLLFAAH
	SCHEMBL12056282	0.83	PTGS1 (0.41)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL12417516	0.83	MTNR1A (0.42)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL15728340	0.83	PTGS1 (0.44)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL10005219	0.82	PTGS1 (0.43)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL13531990	0.82	PTGS1 (0.47)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL10005217	0.82	PTGS1 (0.43)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL16330013	0.81	PTGS1 (0.40)	PTGS1PTGS2MGLLFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.