Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.65 |
| ▸ | LMNA | P02545 | 10/20 | 0.65 |
| ▸ | HTT | P42858 | 6/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20799490 | 0.87 | LMNA (0.60) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL11790568 | 0.85 | ALDH1A1 (0.55) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL242405 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL11792492 | 0.74 | ALDH1A1 (0.49) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL5929729 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL7377635 | 0.74 | KDM4E (0.61) | ALDH1A1NPSR1HPGDKDM4EATM | |
| SCHEMBL20799483 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL11711177 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL13993573 | 0.72 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTNPSR1HPGD | |
| SCHEMBL241594 | 0.71 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | ABL1, FLT3, MAP3K7 | ALDH1A1 2096/4885LMNA 2995/4885HTT 3639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.