SCHEMBL20800810

SCHEMBL20800810

CN(c1ccc(F)cc1)c1cccc2c1oc1c(C3CCCC3)cccc12

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
CEL P19835 2/20 0.31
HTR1D P28221 2/20 0.30
HTR1B P28222 2/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20800820 0.99 CEL (0.33) HTR1AHTR7CELHTR1DHTR1B
SCHEMBL20800883 0.89 HTR1A (0.33) HTR1AHTR7CEL
SCHEMBL20800837 0.89 HTR1A (0.36) HTR1AHTR7CELHTR1DHTR1B
SCHEMBL20800819 0.89
SCHEMBL20650808 0.88 KMT2A (0.36) HTR1AHTR7CEL
SCHEMBL20800885 0.88 CEL (0.33) HTR1AHTR7CEL
SCHEMBL20800844 0.88 HTR1A (0.36) HTR1AHTR7CELHTR1DHTR1B
SCHEMBL21020442 0.86 TRPV1 (0.32) HTR1AHTR7CEL
SCHEMBL20800888 0.86 CEL (0.33) HTR1AHTR7CEL
SCHEMBL21020441 0.86 PSMB5 (0.32) HTR1AHTR7CEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177446-B2 Silicon containing organic fluorescent materials Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-11-16 US disclosed
US-20190081253-A1 SILICON CONTAINING ORGANIC FLUORESCENT MATERIALS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11177446-B2 Silicon containing organic fluorescent materials ORAI2, TRPA1, IK HTR1A 3101/4885HTR7 2572/4885CEL 2192/4885
US-20190081253-A1 SILICON CONTAINING ORGANIC FLUORESCENT MATERIALS ORAI2, TRPA1, IK HTR1A 3101/4885HTR7 2572/4885CEL 2192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.