SCHEMBL20801415

SCHEMBL20801415

O=C(CCC(=O)C1CCCCCCCCC1)ON1C(=O)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PSMB8 P28062 1/20 0.39
▸ HSD11B1 P28845 1/20 0.33
▸ LMNA P02545 1/20 0.32
▸ ALDH1A1 P00352 5/20 0.31
▸ TSHR P16473 2/20 0.31
▸ CES2 O00748 1/20 0.31
▸ CES1 P23141 1/20 0.31
▸ POLB P06746 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ MGLL Q99685 1/20 0.30
▸ CHRM2 P08172 1/20 0.30
▸ CHRM4 P08173 1/20 0.30
▸ CHRM1 P11229 1/20 0.30
▸ CHRM3 P20309 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22181082 0.90 NAAA (0.37) PSMB8HSD11B1ALDH1A1GAA
SCHEMBL24859925 0.90 NAAA (0.37) PSMB8HSD11B1ALDH1A1GAA
SCHEMBL20801354 0.87 PSMB8 (0.36) PSMB8HSD11B1
SCHEMBL24860103 0.87 PSMB8 (0.36) PSMB8HSD11B1
SCHEMBL24859945 0.87 PSMB8 (0.36) PSMB8HSD11B1
SCHEMBL22180984 0.87 PSMB8 (0.36) PSMB8HSD11B1
SCHEMBL22180992 0.87 PSMB8 (0.36) PSMB8HSD11B1
SCHEMBL20801358 0.87 PSMB8 (0.36) PSMB8HSD11B1
SCHEMBL20801584 0.85 PSMB8 (0.33) PSMB8HSD11B1ALDH1A1
SCHEMBL24859939 0.83 PSMB8 (0.32) PSMB8HSD11B1ALDH1A1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11547761-B1 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-01-10 — — US disclosed
US-11110178-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY (US) 2021-09-07 — — US disclosed
US-20200206357-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2020-07-02 — — US disclosed
US-10675358-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-06-09 — — US disclosed
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2019-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200206357-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A PSMB8 2177/4885HSD11B1 2578/4885LMNA 4842/4885
US-10675358-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A PSMB8 2177/4885HSD11B1 2578/4885LMNA 4842/4885
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A PSMB8 2216/4885HSD11B1 2488/4885LMNA 4851/4885
US-11547761-B1 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A PSMB8 2177/4885HSD11B1 2578/4885LMNA 4842/4885
US-11110178-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A PSMB8 2177/4885HSD11B1 2578/4885LMNA 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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