Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828684 | 0.81 | KMT2A (0.71) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL14754066 | 0.80 | KMT2A (0.61) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL19737652 | 0.77 | KMT2A (0.57) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL30928116 | 0.74 | PARP1 (0.76) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL3073571 | 0.74 | PARP1 (1.00) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL8080267 | 0.74 | ALDH1A1 (0.91) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL3082359 | 0.74 | PARP1 (0.85) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL3061740 | 0.73 | PARP1 (1.00) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL31694053 | 0.73 | KMT2A (0.66) | PARP1KMT2ACHEK1MAP2K1MEN1 | |
| SCHEMBL6540956 | 0.73 | KMT2A (0.66) | PARP1KMT2ACHEK1MAP2K1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077762-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077762-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | PARP1 1482/4885KMT2A 3807/4885CHEK1 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.