SCHEMBL208029

SCHEMBL208029

[C]#Cc1ccccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16960000 0.79 CES2 (0.38)
SCHEMBL5475379 0.78 TSHR (0.35)
SCHEMBL29251289 0.77 GRM5 (0.52)
Fluoride SCHEMBL31286347 0.74 GRM5 (0.50)
Charcoal, Activated SCHEMBL31286314 0.74 GRM5 (0.50)
SCHEMBL4351361 0.74
SCHEMBL100446 0.72
SCHEMBL114436 0.72
SCHEMBL28558 0.72
SCHEMBL7990691 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825645-B Naphtho-coumarin compound, preparation method and application of naphthocoumarin compound as photoluminescence material 陕西师范大学 2022-05-13 CN claimed
CN-111825645-A Naphtho-coumarin compound, preparation method and application of naphthocoumarin compound as photoluminescence material 陕西师范大学 2020-10-27 CN claimed
CN-110267950-A Substituted heteroaryl pyrrolones and its salt and its purposes as herbicidal active compounds 拜耳作物科学股份公司 2019-09-20 CN claimed
CN-107531635-A Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-yl sulfonamides or salts thereof and their use for enhancing stress tolerance in plants 拜耳作物科学股份公司 2018-01-02 CN claimed
EP-3256448-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2017-12-20 EP claimed
WO-2016128365-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-18 WO claimed
CN-111825645-B Naphtho-coumarin compound, preparation method and application of naphthocoumarin compound as photoluminescence material 陕西师范大学 2022-05-13 CN disclosed
CN-111825645-A Naphtho-coumarin compound, preparation method and application of naphthocoumarin compound as photoluminescence material 陕西师范大学 2020-10-27 CN disclosed
CN-110267950-A Substituted heteroaryl pyrrolones and its salt and its purposes as herbicidal active compounds 拜耳作物科学股份公司 2019-09-20 CN disclosed
CN-110183488-A A kind of preparation method of 1- naphthols base phosphine oxygen ligand 佛山科学技术学院 2019-08-30 CN disclosed
EP-3098226-B1 BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2018-12-12 EP disclosed
US-10100070-B2 Borate-based base generator, and base-reactive composition comprising such base generator FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2018-10-16 US disclosed
CN-106414461-B Borate-based generated base alkaline agent and alkali reactive composition containing the generated base alkaline agent 富士胶片和光纯药株式会社 2018-09-11 CN disclosed
US-5681836-A Methanesulfonate salts of antipsychotic benzofuran derivatives MERCK, SHARP & DOHME, LTD. (GB) 1997-10-28 US disclosed
US-5665722-A Benzofuran derivatives as D4 receptor antagonists MERCK, SHARP & DOHME, LTD. (GB) 1997-09-09 US disclosed
EP-0757686-A1 BENZOFURAN DERIVATIVES AS D 4? RECEPTOR ANTAGONISTS MERCK SHARP &amp; DOHME LTD. (GB) 1997-02-12 EP disclosed
EP-0443352-B1 Polyimides end-capped with diaryl substituted acetylene NAT STARCH CHEM INVEST (US) 1995-12-06 EP disclosed
WO-1995029911-A1 BENZOFURAN DERIVATIVES AS D4 RECEPTOR ANTAGONISTS MERCK SHARP & DOHME LIMITED (GB) 1995-11-09 WO disclosed
US-5138028-A Composites, molding materials, adhesives, electronics NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1992-08-11 US disclosed
EP-0443352-A2 Polyimides end-capped with diaryl substituted acetylene National Starch and Chemical Investment Holding Corporation (US) 1991-08-28 EP disclosed