Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283514 | 0.80 | HRH4 (0.36) | HRH4HRH3KDM4E | |
| SCHEMBL16330539 | 0.78 | NOS3 (0.39) | — | |
| SCHEMBL9283576 | 0.78 | HRH3 (0.39) | HRH4HRH3KDM4E | |
| SCHEMBL9283512 | 0.76 | HRH3 (0.42) | HRH4HRH3KDM4E | |
| SCHEMBL20096008 | 0.73 | HRH4 (0.40) | HRH4HRH3KDM4E | |
| SCHEMBL15387169 | 0.73 | HRH3 (0.40) | HRH4HRH3KDM4E | |
| SCHEMBL26455568 | 0.72 | PIK3CD (0.32) | — | |
| SCHEMBL8276870 | 0.72 | PIK3CD (0.32) | — | |
| SCHEMBL24927586 | 0.71 | HRH3 (0.39) | HRH4HRH3KDM4E | |
| SCHEMBL24926212 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077803-A1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077803-A1 | TETRACYCLINE COMPOUNDS | TUBB, TUBA1C, TUBA1A | HRH4 3820/4885HRH3 4389/4885KDM4E 2509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.