SCHEMBL2080413

SCHEMBL2080413

COc1ccc(C(=O)OO)c(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.46
RAB9A P51151 3/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 3/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 2/20 0.43
AKR1C3 P42330 2/20 0.43
AKR1C2 P52895 2/20 0.43
POLB P06746 1/20 0.43
CPS1 P31327 1/20 0.42
NR1H4 Q96RI1 1/20 0.42
LPAR1 Q92633 1/20 0.42
CLK1 P49759 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30666384 0.85 ALDH1A1 (0.44) NPC1RAB9ACA1CA2ALDH1A1
SCHEMBL14948225 0.85 ALDH1A1 (0.49) NPC1RAB9ACA1CA2ALDH1A1
SCHEMBL10222517 0.84 AKR1C3 (0.56) NPC1RAB9ACA1CA2ALDH1A1
SCHEMBL12251311 0.83 ALDH1A1 (0.61) NPC1RAB9ACA1CA2ALDH1A1
SCHEMBL195744 0.79 KDM4E (0.40) CA1CA2ALDH1A1HPGDSMN1; SMN2
SCHEMBL2081884 0.79 ALDH1A1 (0.39) NPC1RAB9ACA2ALDH1A1HPGD
SCHEMBL12251364 0.79 NPC1 (0.45) NPC1RAB9ACA1CA2ALDH1A1
SCHEMBL11422801 0.78 NR1H4 (0.49) ALDH1A1MAPK1SMN1; SMN2KMT2AGAA
SCHEMBL17904269 0.77 NPC1 (0.70) NPC1RAB9ACA1CA2ALDH1A1
SCHEMBL12251309 0.76 LMNA (0.66) NPC1RAB9AALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
CN-116323174-A Multilayer sheet comprising a foamed layer suitable for food packaging 北欧化工公司 2023-06-23 CN disclosed
CN-109890892-B High flow heterophasic polypropylene copolymers with improved mechanical and optical properties 博里利斯股份公司 2021-11-16 CN disclosed
CN-106795250-B Process for making graft copolymers on a polyolefin backbone 博里利斯股份公司 2020-06-02 CN disclosed
US-9431172-B2 Biaxially oriented electrical insulating film BOREALIS TECHNOLOGY OY (FI) 2016-08-30 US disclosed
CN-104073190-B Acrylic polymers adhesive composition suitable in extrusion coating paper substrates 北欧化工股份公司 2016-06-29 CN disclosed
CN-104152081-B Be applicable to the acrylic polymers adhesive composition of extrusion coating paper substrates BOREALIS AG (AT) 2016-05-18 CN disclosed
US-8163845-B2 Biaxially oriented electrical insulating film TREOFAN GERMANY GMBH & CO. KG (DE) 2012-04-24 US disclosed
EP-1894715-B1 Biaxially oriented, electrically insulating film TREOFAN GERMANY GMBH & CO KG (DE) 2010-07-28 EP disclosed
US-20100047544-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-02-25 US disclosed
US-20100003489-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-01-07 US disclosed
WO-2008034694-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2008-03-27 WO disclosed
WO-2008025796-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2008-03-06 WO disclosed
EP-1894715-A1 Biaxially oriented, electrically insulating film Treofan Germany GmbH & Co.KG (DE) 2008-03-05 EP disclosed