Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018330 | 0.83 | NPC1 (0.54) | MEN1KMT2AHPGD | |
| SCHEMBL20804235 | 0.82 | HSP90AA1 (0.43) | HSP90AA1POLB | |
| SCHEMBL13114705 | 0.77 | HSP90AA1 (0.56) | HSP90AA1HSD17B2HSD17B1ACHEMEN1 | |
| SCHEMBL18773897 | 0.76 | KMT2A (0.69) | HSP90AA1HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL20804162 | 0.75 | HDAC1 (0.33) | — | |
| SCHEMBL14524623 | 0.74 | HSP90AA1 (0.53) | HSP90AA1HSD17B2HSD17B1MEN1KMT2A | |
| SCHEMBL24011318 | 0.73 | HSP90AA1 (0.52) | HSP90AA1HSD17B2HSD17B1SLC6A2SLC6A4 | |
| SCHEMBL13887741 | 0.73 | RIPK1 (0.54) | HSP90AA1HSD17B2HSD17B1ACHEMEN1 | |
| SCHEMBL16127892 | 0.73 | HSP90AA1 (0.52) | HSP90AA1HSD17B2HSD17B1ACHEMEN1 | |
| SCHEMBL19577474 | 0.72 | SMN1; SMN2 (0.56) | HSP90AA1ACHEMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089962-B1 | RADIOIODINATED COMPOUNDS | NUTECH VENTURES (US) | 2019-03-13 | — | — | EP | disclosed |