Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804235 | 0.77 | HSP90AA1 (0.43) | — | |
| SCHEMBL20804243 | 0.76 | RIPK1 (0.39) | RIPK1MEP1B | |
| SCHEMBL20804153 | 0.75 | HSP90AA1 (0.48) | — | |
| SCHEMBL22018330 | 0.75 | NPC1 (0.54) | RIPK1 | |
| SCHEMBL19577474 | 0.71 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL20804281 | 0.71 | CYP3A4 (0.33) | HDAC1HDAC6RIPK1MEP1B | |
| SCHEMBL25583240 | 0.65 | CASP1 (0.33) | — | |
| SCHEMBL23870240 | 0.63 | TRPA1 (0.42) | — | |
| SCHEMBL4547660 | 0.63 | ACHE (0.42) | HDAC1HDAC6 | |
| SCHEMBL21788814 | 0.62 | CA12 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089962-B1 | RADIOIODINATED COMPOUNDS | NUTECH VENTURES (US) | 2019-03-13 | — | — | EP | disclosed |