Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20804162 | 0.71 | HDAC1 (0.33) | HDAC1HDAC6RIPK1MEP1B | |
| SCHEMBL12657847 | 0.66 | CYP3A4 (0.40) | CYP3A4LMNA | |
| SCHEMBL18893606 | 0.65 | CYP3A4 (0.30) | CYP3A4LMNA | |
| SCHEMBL19402644 | 0.63 | TDP1 (0.36) | CYP3A4LMNA | |
| SCHEMBL22992436 | 0.60 | KDM7A (0.31) | HDAC1 | |
| SCHEMBL22883181 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL13973878 | 0.60 | CA12 (0.35) | CYP3A4LMNA | |
| SCHEMBL10547452 | 0.60 | BMP1 (0.34) | — | |
| SCHEMBL585097 | 0.59 | HDAC1 (0.34) | HDAC1HDAC6 | |
| SCHEMBL23964013 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089962-B1 | RADIOIODINATED COMPOUNDS | NUTECH VENTURES (US) | 2019-03-13 | — | — | EP | disclosed |