Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301188 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL30612315 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL29264869 | 0.86 | PIM1 (0.44) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL10516898 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL14021076 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL14020292 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL18506676 | 0.78 | GPR3 (0.54) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL11545567 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL23954414 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1MAPTNPC1 | |
| SCHEMBL15226937 | 0.74 | MAPT (0.51) | KDM4EALDH1A1L3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158674-B2 | Chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110166366-A1 | Novel Chalcogenoxanthylium Dyes for Purging Blood Pathogens and for Photodynamic Therapy | DETTY MICHAEL R | 2011-07-07 | — | — | US | disclosed |
| US-7906500-B2 | Chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-03-15 | — | — | US | disclosed |
| EP-1688466-B1 | Ink composition, ink jet recording method, printed material, method of producing planographic printing plate, and planographic printing plate | FUJIFILM CORP (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-20060040908-A1 | Novel chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | NIH-DEITR | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166366-A1 | Novel Chalcogenoxanthylium Dyes for Purging Blood Pathogens and for Photodynamic Therapy | ABCB1, ABCC1, GSTP1 | KDM4E 3668/4885ALDH1A1 688/4885L3MBTL1 2891/4885 |
| US-20060040908-A1 | Novel chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | ABCB1, ABCC1, GSTP1 | KDM4E 3668/4885ALDH1A1 688/4885L3MBTL1 2891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.